Protein quantitation using mass spectrometry.
نویسندگان
چکیده
Mass spectrometry is a method of choice for quantifying low-abundance proteins and peptides in many biological studies. Here, we describe a range of computational aspects of protein and peptide quantitation, including methods for finding and integrating mass spectrometric peptide peaks, and detecting interference to obtain a robust measure of the amount of proteins present in samples.
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عنوان ژورنال:
- Methods in molecular biology
دوره 673 شماره
صفحات -
تاریخ انتشار 2010